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Field
Value
Schema
contributor.author
David Male, Ignacio Romero, Jane Loughlin - The Open University
dc
date.accessioned
2010-02-09T15:52:26Z
dc
date.available
2010-02-09T15:52:26Z
dc
identifier.uri
http://dspace.jorum.ac.uk/xmlui/handle/10949/1580
dc
description
A virtual laboratory that includes immuno-gold labelling and transmission electron micrography (immuno-EM). It allows the student to study intracellular-traffic pathways of two cell-surface receptor molecules, following stimulation of the cells with their specific ligand, for different time periods. The programme first introduces the theory underlying the techniques and includes a video of EM work in a real laboratory. The student is then taken through a series of questions which requires them to devise experiments in the virtual laboratory and interpret their electron-micrographs. Immunogold-co-labelling of the receptors and markers of intracellular compartments (Rabs) allows them to track the intracellular movement of the receptors. Data, including EMs can be saved to produce a lab-report. The programme is an installer which places all the files required to run the lab, plus the lab manual (pdf)and a model lab-report (doc) onto the hard-drive in a folder 'BioUKoer - Open University S377 Molecular and cell biology’. The laboratory programme is an executable file, written in C++.
dc
publisher
Open University
dc
rights
Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales
dc
rights.uri
http://creativecommons.org/licenses/by-nc-sa/2.0/uk/
dc
subject
bioukoer
dc
subject
electron microscopy
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subject
immuno-gold labelling
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subject
intracellular compartments
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subject
intracellular traffic
dc
subject
cell surface receptors
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subject
rab gtpases
dc
title
Virtual laboratories in Molecular and Cell Biology - Immuno-electron-microscopy
dc
audience
HE
dc
subject.jacs3
Biological sciences
dc
subject.jacs3code
C000
dc
oer
true
jmd
resourceclass
File
jmd
community
Higher Education
jmd


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Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Except where otherwise noted, this item's license is described as Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales

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